Table 1.

Effects of NaHS Treatment on Liver IL-6, IL-10, cGMP, NO, H₂S Levels in Rats With CP-Induced Hepatotoxicity

	Control	CP	NaHS25	NaHS50	NaHS100
IL-6 pg mg−1 total protein	299.40 ± 27.69	485.58 ± 18.91 ***	395.84 ± 10.46 x **	301.70 ± 15.57 xxx&&	431.22 ± 10.27 +++ ***
IL-10 pg mg−1 total protein	182.60 ± 20.39	401.68 ± 26.99	323.45 ± 14.98 x ***	240.06 ± 13.94 & xxx	372.45 ± 13.32 +++ ***
cGMP pmol. mg−1 total protein	84.89 ± 4.34	41.59 ± 4.13 ***	51.23 ± 4.07 ***	62.29 ± 3.25 xx **	48.24 ± 3.19 ++ ***
NO µmol mg−1 total protein	0.049 ± 0.005	0.016 ± 0.002	0.029 ± 0.002 x ***	0.039 ± 0.002 xxx	0.022 ± 0.001 ++ ***
H 2 S µmol g−o total protein	1.30 ± 0.18	0.93 ± 0.28	1.10 ± 0.06 ##	1.26 ± 0.13 #	2.06 ± 0.22 xx *

Data are given as mean ± SEM. *P < .05, **P < .01, ***P < .001 vs. control group, ^x P ˂˂.05, ^xx P < .01, ^xxx P < .001 vs. CP group, ^& P < .05, ^&& P < .01, ^&&& P < .001 vs. NaHS25 group, ⁺ P < .05, ⁺⁺ P < .01, ⁺⁺⁺ P < .001 vs. NaHS50 group, ^# P < .05, ^## P < .01, ^### P < .001 vs. NaHS100 group. ANOVA (n = 8). ANOVA, analysis of variance; C; Control CP; Cyclophosphamide, NaHS; Sodium hydrosulfide; SEM, standard error of mean.