Table 2.
Association between baseline clinical characteristics, CMR findings and incidence of HFimpEF by logistic regression
Variables | Beta | SE | HR | 95% CI | P value |
Clinical | |||||
Age | −0.020 | 0.009 | 0.980 | 0.964 to 0.997 | 0.023 |
Female | 1.017 | 0.218 | 2.765 | 1.805 to 4.236 | <0.001 |
Baseline LVEF | 0.044 | 0.014 | 1.045 | 1.017 to 1.074 | 0.002 |
Diabetes mellitus | −0.489 | 0.290 | 0.613 | 0.348 to 1.082 | 0.091 |
HbA1c | −0.025 | 0.010 | 0.975 | 0.955 to 0.995 | 0.017 |
Hypertension | −0.111 | 0.211 | 0.895 | 0.593 to 1.353 | 0.600 |
Hypercholesterolaemia | 0.022 | 0.233 | 1.022 | 0.648 to 1.614 | 0.924 |
Cerebrovascular event | −0.281 | 0.326 | 0.755 | 0.399 to 1.430 | 0.389 |
Atrial fibrillation | −0.397 | 0.223 | 0.672 | 0.434 to 1.041 | 0.075 |
Current smoker | −0.447 | 0.291 | 0.639 | 0.362 to 1.130 | 0.124 |
Townsend Deprivation Index | 0.055 | 0.029 | 1.057 | 0.998 to 1.120 | 0.061 |
QRISK3 | −0.024 | 0.008 | 0.977 | 0.962 to 0.992 | 0.003 |
Time between echocardiography and CMR | 0.002 | 0.001 | 1.002 | 1.000 to 1.004 | 0.029 |
Tissue characteristic | |||||
Ischaemic LGE | −1.459 | 0.357 | 0.233 | 0.115 to 0.468 | <0.001 |
Number of segments of ischaemic LGE | −0.064 | 0.126 | 0.938 | 0.732 to 1.200 | 0.610 |
Inducible ischaemia | −0.946 | 0.560 | 0.388 | 0.129 to 1.165 | 0.091 |
Number of segments of inducible ischaemia | −0.142 | 0.222 | 0.867 | 0.562 to 1.339 | 0.520 |
Non-ischaemic LGE | −0.535 | 0.237 | 0.586 | 0.368 to 0.932 | 0.024 |
Number of segments of non-ischaemic LGE | −0.205 | 0.134 | 0.815 | 0.626 to 1.060 | 0.127 |
P-values set in bold indicate statistical significance.
CMR, cardiac magnetic resonance; HbA1c, glycated haemoglobin; HFimpEF, heart failure with improved ejection fraction; LGE, late gadolinium enhancement; LVEF, left ventricular ejection fraction.