Table 3.
values of 5Me3F4AP: Hill and Woodhull parameters.
| Hill parameters | Woodhull parameters | ||||
|---|---|---|---|---|---|
| Compound | pH | (95% C.I.) (in μM) | IC50 (at V=0) ± s.d. (in μM) | δ ± s.d. | n |
| 5Me3F4AP | 6.4 | 220 (190–251) | 118 ± 17 | 0.39 ± 0.04 | 4 |
| 7.4 | 301 (261–341) | 161 ± 25 | 0.40 ± 0.02 | 6 | |
| 9.1 | 693 (523–863) | 373 ± 84 | 0.40 ± 0.04 | 5 | |
| 4AP | 6.8 | 295 (224–366) | 178 ± 5 | 0.41 ± 0.06 | 4 |
| 7.4 a | 293 (258–328) | 155 ± 12 | 0.41 ± 0.08 | 6 | |
| 9.1 | 65 (59–70) | 33 ± 1 | 0.41 ± 0.05 | 4 | |
| 3F4AP | 6.8 | 122 (117–128) | 65 ± 3 | 0.41 ± 0.03 | 5 |
| 7.4 a | 244 (185–303) | 122 ± 4 | 0.46 ± 0.10 | 5 | |
| 9.1 | 370 (323–417) | 159 ± 14 | 0.52 ± 0.02 | 4 | |
| 3Me4AP | 6.8 | 66 (58–75) | 44 ± 1 | 0.28 ± 0.10 | 6 |
| 7.4 a | 40 (36–43) | 21 ± 1 | 0.43 ± 0.10 | 4 | |
| 9.1 | 22 (19–24) | 10 ± 1 | 0.47 ± 0.03 | 5 | |
values were determined at 40mV. A Hill parameter of h≈1 was obtained during the fitting of the data for all experimental conditions.
a
Data at this pH condition has been reported previously (Rodriguez-Rangel et al., 2020).