Table 2.
Factors that change Redox Ratio in ME49 T. gondii infected cells.
| ORR | Oxidized in infected cells |
|---|---|
| NAD(P)H Bound | Increase in Infected cells until 24 HPI |
| NAD(P)H Free | Decrease in Infected cells until 24 HPI |
| NAD(P)H τm | Increase in Infected cells until 24 HPI |
| Mitochondrial respiration | Does not change significantly during time course infection |
| Mitochondrial ATP production | Low. Does not change significantly during time course infection |
| Proton Leak | Low. Does not change significantly during time course infection |
| Non-mitochondrial Oxygen consumption | Increased progressively until 36 HPI, Collapsed at 48 HPI |
| Glycolysis | Increase until 24 HPI, then start reducing progressively. |
| Reactive Oxygen species (ROS) | High at 24 HPI. |
| Intracellular glucose | Increase until 9HPI, then reduce progressively |
| Extracellular Glucose | Fluctuate over infection |
| Intracellular Lactate | High production. Increase until 6 HPI, then reduce progressively |
| Extracellular Lactate | Increase over infection time. |