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[Preprint]. 2023 Aug 13:2023.08.09.552661. [Version 1] doi: 10.1101/2023.08.09.552661

Figure 7: NAC partially ameliorates MC-RR induced damage in spheroids and EHBDs.

Figure 7:

A) Lumen closure in neonatal EHBD cholangiocyte spheroids treated with 300 nM MC-RR plus or minus NAC. B) Lumen closure in neonatal EHBD cholangiocyte spheroids treated with 400 nM MC-RR plus or minus NAC. C) Representative images showing MC-RR-induced EHBD damage at different MC-RR concentrations and in the presence of NAC. D) Quantification of EHBD explant damage after treatment with increasing MC-RR concentrations with and without NAC. Numbers of explants examined per condition are in parentheses. Red: KRT19, Blue: DAPI. All scale bars 50 μm.