Table 1.
Characteristics of patients with/without perianal lesions at the diagnosis of Crohn’s disease
| Parameters | Patients with perianal lesions [N = 324], n [%] |
Patients without perianal lesions [N = 338], n [%] |
p-Value | |
|---|---|---|---|---|
| Gender | Male | 233 [71.9] | 219 [64.8] | p = 0.055 |
| Female | 91 [28.1] | 119 [35.2] | ||
| Age at diagnosis of CD | Mean [SD] | 25.6 [9.3] | 32.9 [15.1] | p < 0.001* |
| Median [min–max] | 23.0 [13–73] | 28.0 [14–86] | ||
| ≤16 years | 30 [9.3] | 28 [8.3] | p < 0.001* | |
| ≥17 to <40 years | 268 [82.7] | 209 [61.8] | ||
| ≥40 to <65 years | 25 [7.7] | 86 [25.4] | ||
| ≥65 years | 1 [0.3] | 15 [4.4] | ||
| <40 years | 298 [92.0] | 237 [70.1] | p < 0.001* | |
| ≥40 years | 26 [8.0] | 101 [29.9] | ||
| Diagnosis of CD | Definite | 306 [94.4] | 312 [92.3] | p = 0.348 |
| Suspected | 18 [5.6] | 25 [7.4] | ||
| BMI [kg/m2] | Number of patients | 259 | 258 | |
| Mean ± SD | 20.41 ± 3.63 | 20.67 ± 3.36 | p = 0.396 | |
| Smoking history# | Number of patients | 72 | 66 | |
| No history of smoking | 49 [68.1] | 45 [68.2] | p = 0.947 | |
| Current smoker | 11 [15.3] | 9 [13.6] | ||
| Has smoked in the past | 12 [16.7] | 12 [18.2] | ||
| Alcohol history# | Number of patients | 72 | 66 | |
| Did not drink/stopped drinking | 29 [40.3] | 29 [43.9] | p = 0.609 | |
| Hardly drinks | 28 [38.9] | 19 [28.8] | ||
| Occasional | 11 [15.3] | 14 [21.2] | ||
| Drinks frequently | 4 [5.6] | 4 [6.1] | ||
| Social background | Student | 124 [38.3] | 76 [22.5] | p = 0.004* |
| Company employee | 142 [43.8] | 165 [48.8] | ||
| Corporate Officer | 4 [1.2] | 6 [1.8] | ||
| Officers and employees of private organizations | 2 [0.6] | 2 [0.6] | ||
| Civil servants | 6 [1.9] | 11 [3.3] | ||
| Faculty member | 3 [0.9] | 3 [0.9] | ||
| Self-employed | 8 [2.5] | 10 [3.0] | ||
| Housewife | 14 [4.3] | 25 [7.4] | ||
| Others | 10 [3.1] | 23 [6.8] | ||
| Unemployed | 11 [3.4] | 15 [4.4] | ||
| Unknown/not specified | 0 [0.0] | 2 [0.6] | ||
Abbreviations: BMI, body mass index; CD, Crohn’s disease; SD, standard deviation.
Details on perianal lesion were unknown for ten patients, which are not included here.
All data are presented as n [%] unless otherwise stated. The denominator for the proportion of patients with or without perianal lesion includes all patients.
The p-values are calculated using the chi-square test [age at diagnosis—Modified Montreal classification, smoking history, alcohol history, social background], Fisher’s exact test [gender, age at diagnosis—Vienna classification, diagnosis of CD] and t-test [mean age at diagnosis, BMI].
#At informed consent—however, data were collected within 3 months from the diagnosis of CD.
*p < 0.05.