Table 3.

Hydropathy scale of different amino acids with 4.5 being the most hydrophobic and −4.5 the most hydrophilic residue (Table adapted from [22]).

Residue	Hydropathy index
Ile	4.5
Val	4.2
Leu	3.8
Phe	2.8
Cys	2.5
Met	1.9
Ala	1.8
Gly	−0.4
Thr	−0.7
Ser	−0.8
Trp	−0.9
Tyr	−1.3
Pro	−1.6
His	−3.2
Glu	−3.5
Gln	−3.5
Asp	−3.5
Asn	−3.5
Lys	−3.9
Arg	−4.5