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. 2023 Aug 21;21:316. doi: 10.1186/s12916-023-03018-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Statistically significant associations between micronutrient levels and cancer outcomes in cancer consortia studies. Associations are listed in ascending order of p-values in the inverse variance-weighted model. The forest plot represents the pooled odds ratio under the inverse variance-weighted model. For the association supported by 1 instrumental variable (vitamin B6-triple negative breast cancer association), the Wald ratio was used instead of the pooled inverse variance weighted odds ratio. A weighted median analysis was not available for the associations supported by two or fewer instrumental variables. Details of all the statistical results are shown in Supplementary table 3. Abbreviations: CI, confidence interval; HER2, human epidermal growth factor receptor 2; NSNP, number of single-nucleotide polymorphisms.