Table 1.
Basic data and ocular surface evaluation of three groups
PBC (n = 19) | DILI (n = 18) | HBV (n = 23) | Control (n = 30) | F | P | |
---|---|---|---|---|---|---|
Sex (male: female) | 4: 15 | 2: 16 | 10: 13 | 12: 18 | – | – |
Age (years) | 56.00 ± 6.47 | 51.83 ± 3.68 | 53.7 ± 5.09 | 52.77 ± 7.84 | 1.600 | 0.20 |
SPEED score | 5.37 ± 2.61 | 7.00 ± 4.51 | 7.74 ± 3.35 | 1.33 ± 1.24 | 24.544 | 0.00 |
First NITBUT (s) | 3.65 ± 1.18 | 3.41 ± 0.74 | 4.33 ± 1.89 | 8.83 ± 3.02 | 38.496 | 0.00 |
Average NITBUT (s) | 5.36 ± 2.74 | 5.10 ± 1.15 | 7.19 ± 3.56 | 10.92 ± 2.76 | 23.650 | 0.00 |
TMH (mm) | 0.21 ± 0.05 | 0.20 ± 0.04 | 0.26 ± 0.05 | 0.25 ± 0.04 | 10.341 | 0.00 |
MG dropout of upper eyelid (%) | 30.3 ± 11.45 | 24.28 ± 5.38 | 23.19 ± 8.83 | 17.95 ± 4.89 | 9.843 | 0.00 |
MG dropout of lower eyelid (%) | 22.06 ± 10.9 | 28.25 ± 10.58 | 21.32 ± 9.12 | 16.80 ± 4.76 | 6.536 | 0.00 |
MG dropout score | 2.79 ± 0.79 | 3.00 ± 0.69 | 2.78 ± 0.67 | 2.10 ± 0.31 | 10.673 | 0.00 |
CFS (score) | 1.95 ± 1.65 | 0.56 ± 1.2 | 0.43 ± 0.95 | 0 ± 0.00 | 14.128 | 0.00 |
Schirmer I test (mm) | 4.11 ± 5.00 | 11.33 ± 7.12 | 10.61 ± 6.75 | 15.15 ± 10.18 | 7.673 | 0.00 |
LLT (nm) | 87.05 ± 8.26 | 67.44 ± 14.83 | 83.3 ± 12.55 | 84.53 ± 14.06 | 9.086 | 0.00 |
Meibum expressibility score | 0.05 ± 0.23 | 1.94 ± 0.54 | 2.09 ± 0.73 | 0.07 ± 0.25 | 126.229 | 0.00 |
Meibum quality score | 0.37 ± 1.12 | 6.67 ± 2.57 | 4.87 ± 2.42 | 0.03 ± 0.18 | 76.880 | 0.00 |
Total blinking, n | 8.79 ± 3.51 | 10.44 ± 2.85 | 8.96 ± 3.17 | 7.53 ± 2.06 | 3.954 | 0.01 |
PBR (%) | 92.69 ± 22.85 | 60.08 ± 10.47 | 80.33 ± 12.82 | 53.31 ± 21.75 | 22.419 | 0.00 |
NIKBUT, noninvasive breakup time; TMH, tear meniscus height; MG, meibomian gland; CFS, corneal fluorescein staining; LLT, lipid layer thickness; PBR, partial blinking rate