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. 2023 Jun 23;12(5):2493–2503. doi: 10.1007/s40123-023-00747-4

Table 1.

Basic data and ocular surface evaluation of three groups

PBC (n = 19) DILI (n = 18) HBV (n = 23) Control (n = 30) F P
Sex (male: female) 4: 15 2: 16 10: 13 12: 18
Age (years) 56.00 ± 6.47 51.83 ± 3.68 53.7 ± 5.09 52.77 ± 7.84 1.600 0.20
SPEED score 5.37 ± 2.61 7.00 ± 4.51 7.74 ± 3.35 1.33 ± 1.24 24.544 0.00
First NITBUT (s) 3.65 ± 1.18 3.41 ± 0.74 4.33 ± 1.89 8.83 ± 3.02 38.496 0.00
Average NITBUT (s) 5.36 ± 2.74 5.10 ± 1.15 7.19 ± 3.56 10.92 ± 2.76 23.650 0.00
TMH (mm) 0.21 ± 0.05 0.20 ± 0.04 0.26 ± 0.05 0.25 ± 0.04 10.341 0.00
MG dropout of upper eyelid (%) 30.3 ± 11.45 24.28 ± 5.38 23.19 ± 8.83 17.95 ± 4.89 9.843 0.00
MG dropout of lower eyelid (%) 22.06 ± 10.9 28.25 ± 10.58 21.32 ± 9.12 16.80 ± 4.76 6.536 0.00
MG dropout score 2.79 ± 0.79 3.00 ± 0.69 2.78 ± 0.67 2.10 ± 0.31 10.673 0.00
CFS (score) 1.95 ± 1.65 0.56 ± 1.2 0.43 ± 0.95 0 ± 0.00 14.128 0.00
Schirmer I test (mm) 4.11 ± 5.00 11.33 ± 7.12 10.61 ± 6.75 15.15 ± 10.18 7.673 0.00
LLT (nm) 87.05 ± 8.26 67.44 ± 14.83 83.3 ± 12.55 84.53 ± 14.06 9.086 0.00
Meibum expressibility score 0.05 ± 0.23 1.94 ± 0.54 2.09 ± 0.73 0.07 ± 0.25 126.229 0.00
Meibum quality score 0.37 ± 1.12 6.67 ± 2.57 4.87 ± 2.42 0.03 ± 0.18 76.880 0.00
Total blinking, n 8.79 ± 3.51 10.44 ± 2.85 8.96 ± 3.17 7.53 ± 2.06 3.954 0.01
PBR (%) 92.69 ± 22.85 60.08 ± 10.47 80.33 ± 12.82 53.31 ± 21.75 22.419 0.00

NIKBUT, noninvasive breakup time; TMH, tear meniscus height; MG, meibomian gland; CFS, corneal fluorescein staining; LLT, lipid layer thickness; PBR, partial blinking rate