Table 2. Serological evaluation of antigens for diagnosis of leishmaniasis.

Antigen	Sensitivity (CI 95%; N = 119)	Sensitivity (%)			Specificity (CI 95%; N = 67)	Specificity (%)					LR
		Sym. (N = 50)	Asy. (N = 50)	CoInfec (N = 19)		Bab. (N = 7)	Ehr. (N = 6)	T. cruzi (N = 20)	NI (N = 34)	AC (%)
rDyn-1 protein	100.0 0.969 to 1.00	100.0	100.0	100.0	97.01 0.8963 to 0.996	71.43	100.0	100.0	100.0	98.92	33.50
Mix peptides	98.32 0.940 to 0.998	100.0	98.00	94.74	98.51 0.9196 to 0.999	100.0	83.33	100.0	100.0	98.39	65.87
rKDDR-plus protein	99.16 0.954 to 0.999	100.0	98.00	100.00	95.52 0.8747 to 0.990	71.43	100.0	95.00	100.00	97.85	22.15
K-plus 1 peptide	98.32 0.940 to 0.998	100.0	100.0	89.47	94.03 0.8541 to 0.983	100.0	66.67	95.00	97.06	96.77	16.47
Dyn-1 peptide	99.16 0.954 to 0.999	100.0	100.0	94.74	88.06 0.7782 to 0.947	100.0	100.0	60.00	100.0	95.16	8.3
Crude extract	95.8 0.904 to 0.986	98.00	94.00	94.74	85,07 0.7426 to 0.926	71.43	100.0	65.00	97.06	91.94	6.4
rK39	94.96 0.893 to 0.981	98.00	94.00	89.47	83.58 0.7252 to 0.915	71.43	66.67	85.00	88.24	90.86	5.78
K-plus 2 peptide	91.6 0.8509 to 0.9590	94.00	90.00	89.47	47.76 0.3540 to 0.603	57.14	33.33	65.00	38.24	75.81	1.75

Abbreviations: CI: confidence interval, Sym.: symptomatic, Asy.: asymptomatic, CoInfec: coinfected, Bab.: Babesia sp., Ehr: Ehrlichia sp., NI: not infected, AC: accuracy LR: likelihood.