Table 1.
Main clinical and biochemical characteristics of children and adolescents with type 1 diabetes
All (n = 278) | |
---|---|
Age | 14.52 ± 2.99 |
Years of diabetes | 7.55 ± 3.58 |
Body height (cm) | 161.1 ± 13.8 |
Body weight (kg) | 56.45 ± 15.70 |
BMI | 21.29 ± 3.65 |
BMI z-score | 0.40 ± 0.90 |
SBP (mmHg) | 107.55 ± 10.72 |
SBP percentile | 36.0 [17.7–57.5] |
DBP (mmHg) | 68.25 ± 7.33 |
DBP percentile | 60.6 [44.6–77.5] |
HbA1c (%) | 8.0 [7.4–8.5] |
HbA1c (mmol/mol) | 64 [57–69] |
Serum Creatinine (mg/dL) | 0.64 ± 0.15 |
eGFR (mL/min) | 108.22 ± 20.17 |
ACR (mg/mmol) (n = 225) | 0.37 [0.20–0.70] |
PPARG rs1801282 | |
GG, n (%) | 3(1.1) |
CG, n (%) | 33(11.9) |
CC, n (%) | 242(87.1) |
IGF1 rs35767 | |
GG, n (%) | 191(68.7) |
AG, n (%) | 72(25.9) |
AA, n (%) | 15(5.4) |
PPARG + IGF1 | 2.23 ± 0.70 |
Sample size, n = 278, otherwise indicated. Data are expressed as means ± SD, medians [IQR] or number and percentages
BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, ACR albumin-to-creatinine ratio