Table 3.
Clinical and anthropometrics characteristics in study subjects according to PPARG (rs1801282) genotypes
| CC (n = 242) | CG (n = 33) | GG (n = 3) | p value | |
|---|---|---|---|---|
| Age | 14.42 ± 3.00 | 15.26 ± 2.89 | 14.83 ± 2.33 | 0.309 |
| Males, n (%) | 121 (50.0) | 25 (75.8) | 0 (0) | 0.004 |
| Years of diabetes | 7.49 ± 3.60 | 8.16 ± 3.39 | 6.02 ± 5.10 | 0.437 |
| Body height (cm) | 160.6 ± 13.7 | 165.0 ± 14.5 | 160.3 ± 5.5 | 0.130 |
| Body weight (kg) | 56.05 ± 15.78 | 58.67 ± 14.86 | 64.33 ± 20.60 | 0.380 |
| BMI | 21.27 ± 3.68 | 21.13 ± 3.12 | 24.66 ± 6.25 | 0.550 |
| BMI z-score | 0.41 ± 0.90 | 0.29 ± 0.88 | 0.95 ± 1.00 | 0.548 |
| SBP (mmHg) | 107.3 ± 10.3 | 108.8 ± 13.3 | 111.7 ± 18.9 | 0.693 |
| SBP percentile | 40.0 ± 26.4 | 36.5 ± 27.1 | 59.7 ± 47.5 | 0.489 |
| DBP (mmHg) | 68.4 ± 7.3 | 67.6 ± 7.5 | 67.7 ± 9.3 | 0.639 |
| DBP percentile | 59.8 ± 20.9 | 57.1 ± 21.0 | 58.1 ± 26.7 | 0.742 |
| HbA1c (%) | 8.0 ± 0.9 | 8.3 ± 0.9 | 8.3 ± 1.8 | 0.163 |
| Serum creatinine (mg/dL) | 0.64 ± 0.15 | 0.68 ± 0.16 | 0.51 ± 0.11 | 0.088 |
| eGFR (mL/min) | 108.4 ± 20.0 | 104.3 ± 20.0 | 133.8 ± 27.3 | 0.047 |
| ACR (mg/mmol) | 0.98 ± 1.99 | 0.90 ± 1.90 | 0.56 ± 1.56 | 0.512 |
Data are expressed as means ± SD. Differences among groups were tested by Kruskal–Wallis’s test
Bold value represents statisically significant result
BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, ACR albumin-to-creatinine ratio