Table 2.
Differences in mean Psoriasis Treatment Convenience Scale total scores at week 1 and week 8
Week 1 | Week 8 | |||||||
---|---|---|---|---|---|---|---|---|
PAD-cream | TS/gel | Difference | P value | PAD-cream | TS/gel | Difference | P value | |
All patients, n = 1271 | 39.1 | 36.4 | 2.7 | < 0.0001 | 40.4 | 37 | 3.4 | < 0.0001 |
BSA > 10% subgroup, n = 319 | 39.7 | 36.0 | 3.7 | < 0.0001 | 41.3 | 37.7 | 3.6 | < 0.0001 |
mPASI > 10 subgroup, n = 288 | 40.7 | 37.0 | 3.7 | < 0.0001 | 40.5 | 36 | 4.5 | < 0.0001 |
DLQI > 10 subgroup, n = 505 | 38.7 | 34,7 | 4.0 | < 0.0001 | 39.3 | 35.3 | 4.0 | < 0.0001 |
Rule of tens subgroup,a n = 705 | 39.0 | 35.1 | 3.8 | < 0.0001 | 39.7 | 35.9 | 3.8 | < 0.0001 |
High severity subgroup,b n = 104 | 38.9 | 35.4 | 3.5 | 0.0196 | 41.7 | 36.3 | 5.5 | 0.0001 |
MITT using last observation carried forward, while-on-treatment strategy. Differences and p values are for CAL/BDP PAD-cream vs. CAL/BDP TS/gel
TS topical suspension, MITT modified intention to treat, BSA body surface area, mPASI modified Psoriasis Area and Severity Index, DLQI Dermatology Life Quality Index, CAL calcipotriene, BDP betamethasone dipropionate, PAD polyaphron dispersion
aRule of tens subgroup = BSA or mPASI or DLQI > 10
bHigh severity subgroup = BSA and mPASI and DLQI > 10