Table 2.
Stage at diagnosis | Survival | |||
---|---|---|---|---|
Association | Significant | Non-significant | Significant | Non-significant |
Patient interval | 2 studies (31, 56)† (intervals >60 and > 90 days, respectively) | 3 studies (32, 46, 54) | Not studied | Not studied |
Diagnostic interval | 1 study (31)† (intervals >30 days) | 3 studies (32, 46, 54) | Not studied | Not studied |
Treatment interval | 2 studies (40, 55)† (longer intervals and intervals >20 days, respectively) | 4 studies (37, 39, 46, 54) | 3 studies [37,40,41]†† (intervals >20, >20 and > 45 days, respectively) | 2 studies (39, 55) |
†Studies finding a significant positive association (i.e., longer intervals were associated with more advanced stages at diagnosis). ††Studies finding a significant negative association (i.e., longer intervals were associated with lower survival).