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Comparison of estimated mutation rates for various influenza virus strains
| Virus | Reference | Assay | Gene | Mutation rate (bp/site/replication) |
|---|---|---|---|---|
| A/Victoria/3/75 (H3N2) | 28 | Monoclonal antibody escape | HA | 1.0 × 10−5 |
| A/WSN/33 (H1N1) | 21;2 | Direct sequencing of RNA | NS | 0.84 × 10−5 |
| A/Mallard/New York/6750/78 (H2N2) | This study | Amantadine escape | M | 3.2 × 10−5 |
| A/Swine/Germany/2/81 (H1N1) | This study | Amantadine escape | M | 0.68 × 10−5 |
