Table 3.
Multivariable-adjusted Odds Ratios (95%CIs) for Circulating Caprylic Acid Level and Risk of Incident AD among Participants with MCI at Baseline
| Caprylic acid (C8:0)1 | No. of cases/all | Odds Ratio (95%CI) | Odds Ratio (95%CI) Per STD | P Value |
|---|---|---|---|---|
|
| ||||
| All MCI participants at baseline | ||||
| Model 1 | 1.04 (0.89–1.22) | 1.03 (0.91–1.18) | 0.6258 | |
| Model 2 | 210/392 | 1.06 (0.89–1.25) | 1.04 (0.91–1.19) | 0.5216 |
| Model 3 | 1.05 (0.89–1.24) | 1.04 (0.91–1.19) | 0.5361 | |
Circulating C8:0 level was log transformed. Model 1 presented crude values; model 2 was adjusted for age, sex, race, ethnicity, education years, and APOE ε4 alleles; model 3 was additionally adjusted for type 2 diabetes, hypertension, stroke, cardiovascular disease, and metabolic diseases.
P<0.05
P<0.01
P<0.001.
Abbreviations: MCI, significant memory concern; AD, Alzheimer's Disease; STD, standard deviation.