Table III.

Time course properties of cowhage-induced itch

Visit	Saline	Botox®
Peak itch (itch VAS, mean ± SEM)
Baseline	7.2 ± 0.32	7.4 ± 0.34
1 week	7.4 ± 0.33	6.2 ± 0.39
1 month	7.1 ± 0.33	6.1 ± 0.38
3 months	6.6 ± 0.34	5.7 ± 0.41
Peak itch time (s, mean ± SEM)
Baseline	62.7 ± 26.5	62.7 ± 5.75
1 week	58.2 ± 4.64	62.2 ± 4.75
1 month	60.0 ± 4.61	60.0 ± 4.57
3 months	60.0 ± 5.30	63.6 ± 6.02
Itch duration (s, mean ± SEM)
Baseline	316.3 ± 17.88	301.7 ± 17.26
1 week	297.1 ± 16.64	254.6 ± 15.96
1 month	269.1 ± 16.80	246.2 ± 13.92
3 months	283.6 ± 13.95	261.2 ± 12.95

VAS: visual analog scale; SEM: standard error of mean.