Table 3.
Chlamydia, gonorrhea, syphilis, and HIV incidence during time on PrEP and time not on PrEP among participants in the COPE study for young men who have sex with men and transgender women who exchange sex, Thailand (2018–2020) (n = 844).
| Infection detected | Incident cases | Incidence per 100 PY | (95% CI) | Incidence rate ratio | (95% CI) | p-value |
|---|---|---|---|---|---|---|
| Chlamydia trachomatis | ||||||
| On PrEP | 192 | 32.3 | (27.9, 37.2) | 1.64 | (1.18, 2.33) | 0.002 |
| Not on PrEP | 44 | 19.7 | (14.3, 26.4) | |||
| Neisseria gonorrhoeae | ||||||
| On PrEP | 79 | 13.3 | (10.5, 16.6) | 2.48 | (1.34, 5.00) | 0.002 |
| Not on PrEP | 12 | 5.4 | (2.8, 9.4) | |||
| Treponema pallidum | ||||||
| On PrEP | 76 | 12.8 | (10.1, 16.0) | 1.35 | (0.82, 2.30) | 0.269 |
| Not on PrEP | 21 | 9.5 | (5.9, 14.5) | |||
| HIV | ||||||
| On PrEP | 0 | 0.00 | (0.00, 0.62) | 0.00 | (0.00, 0.22) | <0.001 |
| Not on PrEP | 10 | 3.42 | (1.64, 6.30) |
PrEP, HIV pre-exposure prophylaxis; PY, person-years; CI, confidence interval; 95% confidence intervals and p-values from exact tests.