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. 2022 May 2;28(5):607–614. doi: 10.14744/tjtes.2021.30434

Table 3.

Results of the receiver operating characteristic analysis and sensitivity, specificity

Negative appendectomy / Positive appendicitis Uncomplicated AA/ Complicated AA


AUC 95% CI p Cut off Sensitivity Specificity AUC 95% CI p Cut off Sensitivity Specificity
WBC 0.746 0.665–0.826 <0.001 13.52 57.6% 84.0% 0.658 0.573–0.744 0.001 14.84 71.8% 58.1%
PLT 0.413 0.302–0.524 0.148 350.00 6.8% 100.0% 0.548 0.450–0.647 0.327 302.50 33.3% 82.4%
Neutrophil 0.771 0.691–0.851 <0.001 9.135 68.7% 80.0% 0.682 0.595–0.769 <0.001 12.945 56.4% 69.7%
Lymphocyte 0.359 0.238–0.480 0.019 0.735 95.4% 8.0% 0.289 0.196–0.381 <0.001 0.575 100.0% 2.1%
Monocyte 0.675 0.576–0.773 0.004 0.785 65.6% 72.0% 0.547 0.457–0.637 0.342 0.835 74.4% 40.5%
RDW–CV 0.561 0.455–0.667 0.309 13.05 29.7% 84.0% 0.561 0.467–0.656 0.215 12.85 46.2% 64.1%
IG 0.687 0.567–0.806 0.002 0.025 88.2% 40.0% 0.737 0.652–0.821 <0.001 0.055 74.4% 60.6%
CRP 0.582 0.462–0.702 0.172 0.75 60.4% 56.0% 0.747 0.656–0.837 <0.001 7.55 56.4% 85.6%
T.BIL 0.607 0.490–0.725 0.073 0.495 77.1% 44.0% 0.610 0.522–0.697 0.026 0.555 87.2% 34.5%
NLR 0.735 0.616–0.854 <0.001 3.686 76.2% 72.0% 0.742 0.653–0.831 <0.001 11.064 56.4% 88.0%
PLR 0.581 0.467–0.695 0.177 171.987 28.5% 88.0% 0.707 0.607–0.806 <0.001 177.651 64.1% 77.8%
NPR (1/10³) 0.789 0.703–0.874 <0.001 46.429 48.9% 96.0% 0.662 0.576–0.749 0.001 47.432 71.8% 58.1%
IGLR (1/10³) 0.712 0.592–0.833 <0.001 8.43 93.5% 48.0% 0.782 0.698–0.865 <0.001 37.038 71.8% 74.3%
MLR 0.700 0.581–0.819 <0.001 0.303 81.1% 56.0% 0.720 0.631–0.808 <0.001 0.738 59.0% 81.3%
RDWLR 0.647 0.523–0.771 0.014 5.207 72.8% 60.0% 0.711 0.617–0.806 <0.001 8.157 66.7% 71.8%

ROC Curve. WBC: White blood cells; PLT: Platelets; RDW-CV: Red blood cell distribution width; IG: Immature granulocyte; CRP: C-reactive protein; T.BIL: Total bilirubin; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; NPR: Neutrophil-to-platelet ratio; IGLR: IG-to-Lymphocyte ratio; MLR: Monocyte-to-Lymphocyte Ratio; RDWLR: red blood cell distribution width-to-lymphocyte ratio; AUC: Area under curve; CI: Confidence interval.