Table 2.
Adjusteda IRRs of CVRFs Among Survivors by Race/Ethnicity
| Hypertension |
Hyperlipidemia |
Diabetes |
Obesity |
Multiple CVRFs |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Number of Events (Rateb) | IRR (95% CI) | Number of Events (Rateb) | IRR (95% CI) | Number of Events (Rateb) | IRR (95% CI) | Number of Events (Rateb) | IRR (95% CI) | Number of Events (Rateb) | IRR (95% CI) | |
| White, non-Hispanic, referent | 1,710 (1.85) | 1.00 | 1,385 (2.01) | 1.00 | 491 (0.42) | 1.00 | 3,415 (2.97) | 1.00 | 1,635 (2.35) | 1.00 |
| Black, non-Hispanic | 139 (2.61) | 1.41 (1.10-1.80) | 55 (1.63) | 0.81 (0.54-1.23) | 51 (0.70) | 1.65 (1.04-2.75) | 352 (5.10) | 1.72 (1.43-2.07) | 129 (3.73) | 1.59 (1.20-2.10) |
| Hispanic | 107 (1.64) | 0.89 (0.67-1.17) | 88 (2.12) | 1.06 (0.78-1.44) | 75 (0.76) | 1.77 (1.23-2.56) | 427 (4.29) | 1.44 (1.24-1.68) | 135 (2.70) | 1.15 (0.89-1.49) |
CVRF = cardiovascular risk factor; IRR = incidence rate ratio.
Using multivariable piecewise exponential regression modeling, adjusted for age, sex, age at diagnosis, baseline household income, educational attainment, marital status, employment, insurance, anthracycline, alkylating agents, and chest-directed radiation therapy.
Adjusted incidence rate per 100 person-years at age 40 from the multivariable model by race/ethnicity. The rates shown are for survivors with the following set of covariate values: sex = male, diagnosis age = 5 to 9 years, income ≥$60,000, employed, insured, never married by baseline, some college or vocational, alkylating agent = yes, anthracycline = yes, and chest radiation therapy = no on the basis of the piecewise-exponential model.