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. Author manuscript; available in PMC: 2023 Aug 22.
Published in final edited form as: Leukemia. 2023 Mar 30;37(5):964–980. doi: 10.1038/s41375-023-01874-4

Table 1.

Association of Dietary Patterns with Multiple Myeloma.

A
Population Meat eaters Fish eaters Vegetarians Vegans
Number 32,491 8612 18,298 2246 Key AJCN 2014 [11]
Cancer cases 3275 520 1098 105
Relative risk reduction 100 88 89 81
Multiple myeloma cases 53 (0.2%) 7 (0.08%) 5 (0.03%)
Relative risk reduction 100 80 23
B
Diet Hazard Ratio (per 1 SD↑) Confidence interval P value Study
Multiple Myeloma in Males
 Unhealthy Dietary Patterns
  Empirical Dietary Inflammatory Pattern (EDIP) 1.16 1.02–1.32 Lee et al. JNCI Can Spec 2019 [12]
Multiple Myeloma Specific Mortality
 Healthy Dietary Patterns
  Alternate Healthy Eating Index-2010 (AHEI) 0.76 0.67–0.87 <0.001 Lee et al. Int J Cancer 2020 [13]
  Alternate Mediterranean diet 0.85 0.75–0.97 0.01
  Dietary Approaches to Stop Hypertension (DASH) diet 0.85 0.76–0.95 0.006
  Prudent diet 0.76 0.66–0.87 <0.001
 Unhealthy Dietary Patterns
  Western diet 1.24 1.07–1.44 0.005
  Empirical Dietary Index for Insulin Resistance (EDIR) 1.16 1.02–1.33 0.03
  Empirical Dietary Index for Hyperinsulinemia (EDIH) 1.17 1.01–1.35 0.03

A:Oxford Vegetarian study and EPIC-Oxford cohort and Multiple Myeloma by Key et al. B:Dietary Patterns and Multiple Myeloma by Lee et al.