Table 2.
Characteristics of patients and interventions performed in the included studies.
Study Number | Patients (Cases vs. Controls) |
Average Age (Years) (Cases vs. Controls) | Gender (Female) (Cases vs. Controls) | Vitamin D Intake (IU) | Duration of Vitamin D Supplementation |
---|---|---|---|---|---|
1 [31] Leis et al. | 197 (105 vs. 92) | NR | 40.8% vs. 42.2% | 48/kg/day vs. 60/kg/day | 6 months |
2 [32] Jensen et al. | 22 (11 vs. 11) | 2.2 vs. 3.1 | 65.6% vs. 72.7% | 1 oral bolus of 50,000 + 400/day | 6 months |
3 [33] Aglipay et al. | 703 (349 vs. 354) | 2.70 vs. 2.76 | 45.2% vs. 39.4% | 2000/day vs. 400/day | 10 months |
4 [34] Hueniken et al. | 703 (349 vs. 354) | 2.70 vs. 2.76 | 45.2% vs. 39.4% | 2000/day vs. 400/day | 4–8 months |
5 [35] Singh et al. | 100 (50 vs. 50) | NR | 44.0% vs. 40.0% | 1 oral bolus of 300,000 + 400/day | 12 months |
6 [36] Ducharne et al. | 47 (23 vs. 24) | 2.9 vs. 2.9 | 30.0% vs. 42.0% | 2 oral boluses of 100,000 (3.5 months apart) | 7 months |
7 [37] Jadhav et al. | 298 (155 vs. 143) | 3.1 vs. 3.2 | 36.2% | 1 oral bolus of 120,000 + 400/day vs. 400/day | 6 months |
8 [38] Xiao et al. | 119 (60 vs. 59) | 4.8 vs. 4.8 | 28.3% vs. 30.5% | 800/day vs. 400/day | 3 months |
NR—not reported; IU—international units; cases—received vitamin D; controls—did not receive vitamin D supplementation.