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Validation of the SMA multiplex assay: determination of sensitivity, specificity, and accuracy. Fifty-four known 0, 1, 2 copy SMN1 controls were tested using the SMA multiplex assay to evaluate its performance.
| Genotype | Samples |
|---|---|
| True Negative | 35 |
| True Positive | 19 |
| False Negative | 0 |
| False Positive | 0 |
| Total valid | 54 |
| Sensitivity | 100% |
| Specificity | 100% |
| Accuracy | 100% |
