Table 2:
Overview of studies reporting HS data.
| Authors | Evaluation tools | Study protocol | Characteristics of patients | Aim of study | Results | Critical Review Form-TOTAL items |
|---|---|---|---|---|---|---|
| Van der Schans et al.(2002)17 | RAND-36 | Cross-sectional study | 437 LLA, 62% TTA. 71% males. Mean age 65±15 years (8% of the sample was older than 75 years) | Describing health-related quality of life in LLA and investigating potential determinants: including phantom pain age, sex, level of amputation, amputation reason, phantom or stump pain and walking distance | Health-related quality of life was positively influenced by a) absence of phantom pain, b) walking distance c) absence of stump pain d) amputation through or above the knee | 12/13 |
| Boutoille et al.(2008)28 | MOS SF-36 | Retrospective case control study | 6 TTA (mean age 68 years) and 9 with a current foot ulcer, (mean age 70 years) | Evaluating the influence of amputation or conservative treatment for a diabetic foot ulcer on physical and social aspects of patients' QoL | TTA group reported less pain but similar QoL compared to foot ulcer patients | 14/15 |
| Fortington et al. (2013)29 | RAND-36 | Longitudinal study. | 82 LLA. Mean age 67.8±13 years. 63% TTA and 37% TFA. A total of 35 remained in the study at 18 months follow up. | Evaluating how the age and walking distance could influence QoL 18 months after the amputation. Comparing QoL of LLA with a control group | Only the domain ±social function± was influenced significantly by the ability to walk. Except for physical function, the other domains were similar to population norm values. The domain ±physical function± was positively correlated to lower levels of amputation and to age categories of less than 65 years. QoL improved after amputation, in particular in the first 6 months | 14/15 |
| Knezevic et al. (2015)30 | RAND-36 | Cross-sectional study | 28 LLA. 61% TFA, 39% TTA. Mean age: 65.4 ± 13.6 years. | Assessing the QoL of the patients with LLA compared to a control group, taking into account the influence of age and level of amputation | TTA are more mobile than TFA. The most significant difference was in the domains "physical functioning" and "general health", with higher scores reported by TTA | 14/15 |
Abbreviations: LLA, lower limb amputees; TTA, transtibial amputees; RAND-36, Research and Development Corporation measure of Quality of Life 36-Item Health Survey 1.0; SF-36, Short-Form General Health Survey; MOS SF-36, Medical Outcomes Study 36-item short-form