Table 2:

Expected capacity (i.e., yes, no) of typical early preliminary (Pre) and full cost-utility analysis (CUA) to address the 19-item Consensus Health Economic Criteria (CHEC) extended checklist.

Item	Questions	CUA
		Early	Pre	Full
1	Is the study population clearly described?	Yes	Yes	Yes
2	Are competing alternatives clearly described?	Yes	Yes	Yes
3	Is a well-defined research question posed in answerable form?	Yes	Yes	Yes
4	Is the economic study design appropriate to the stated objective?	Yes	Yes	Yes
5	Is the chosen time horizon appropriate in order to include relevant costs and consequences?	No	No	Yes
6	Is the actual perspective chosen appropriate?	Yes	Yes	Yes
7	Are all important and relevant costs for each alternative identified?	No	No	Yes
8	Are all costs measured appropriately in physical units?	Yes	Yes	Yes
9	Are costs valued appropriately?	No	No	Yes
10	Are all important and relevant outcomes for each alternative identified?	No	No	Yes
11	Are all outcomes measured appropriately?	No	No	Yes
12	Are outcomes valued appropriately?	No	No	Yes
13	Is an incremental analysis of costs and outcomes of alternatives performed?	No	Yes	Yes
14	Are all future costs and outcomes discounted appropriately?	No	No	Yes
15	Are all important variables, whose values are uncertain, appropriately subjected to sensitivity analysis?	No	No	Yes
16	Do the conclusions follow from the data reported?	Yes	Yes	Yes
17	Does the study discuss the generalizability of the results to other settings and patient/client groups?	Yes	Yes	Yes
18	Does the article indicate that there is no potential conflict of interest of study researcher(s) and funder(s)?	Yes	Yes	Yes
19	Are ethical and distributional issues discussed appropriately?	Yes	Yes	Yes