Figure 1. Expression changes in DM-related genes after strength training.

(A–G) The change in expression, measured as log₂FC from pretraining to posttraining in individuals as compared with unaffected controls from RNA-Seq data, for each study participant for the following DM1-related genes: (A) DMPK; (B) MBNL1; (C) MBNL2; (D) MBNL3; (E) CELF1; (F) CELF2; and (G) CELF3. Values are shown for both individual analysis (black bars) and grouped analysis (red bar). P values were calculated using a quasi-likelihood F test to test for differential expression among pretraining individuals, posttraining individuals, grouped pretraining individuals, and grouped posttraining individuals.