Table 2. Changes in functional connectivity with percent use of bright light therapy.
| Regions | Hemisphere | x | y | z | Size | Size pFDRa | Peak p- |
|---|---|---|---|---|---|---|---|
| Left Frontal Pole Seed | |||||||
| Cerebellum crus 2 | Left | -24 | -90 | -34 | 244 | 0.000325 | 0.000002 |
| Posterior cingulate, precuneus | Left | +18 | -44 | +38 | 144 | 0.006866 | 0.000010 |
| Right Frontal Pole Seed | |||||||
| Cerebellum crus 1, 6, lingula gyrus, occipital pole, fusiform gyrus, intercalcarine cortex | Left | -10 | -80 | -24 | 587 | 0.000000 | 0.000016 |
| Frontal pole | Right, Left | +06 | +66 | +28 | 248 | 0.000060 | 0.000007 |
| Inferior frontal gyrus operculum | Left | -48 | +12 | +08 | 106 | 0.013547 | 0.000048 |
| Middle temporal gyrus, posterior | Left | -60 | -50 | +02 | 96 | 0.013916 | 0.000006 |
| Middle temporal gyrus, anterior | Left | -50 | -22 | -12 | 95 | 0.013916 | 0.000028 |
Pretreatment–post-treatment changes in connectivity of left and right frontal poles during performance of a go / no-go cognitive task that correlated with degree of BLT device use.
aFDR–False Discovery Rate statistical correction for cluster size.