Table 2.
Complicated Intra-abdominal Infection–Specific Desirability of Outcome Ranking Endpoint
DOOR Ranka | Alive? | Count of Eventsb |
---|---|---|
0 (most desirable) | Yes | 0 of 7 |
1 | Yes | 1 of 7 |
2 | Yes | 2 of 7 |
3 | Yes | 3 of 7 |
4 | Yes | 4 of 7 |
5 | Yes | 5 of 7 |
6 | Yes | 6 of 7 |
7 | Yes | 7 of 7 |
8 (least desirable) | No (death) | Any |
Abbreviation: DOOR, desirability of outcome ranking.
Each participant was assigned a DOOR between 0 and 8 by counting the number of events a participant experienced within each component category (see Table 1). Study participants classified as having the outcomes of “indeterminate” or “clinical failure” were counted as having 1 event in the “absence of clinical response” category. Up to 2 events were counted in the categories of infectious complications, surgical/percutaneous procedures, and serious adverse events. These events comprised the final DOOR.
Absence of clinical response: 0 or 1 event; infectious complications: 0, 1, or 2 events; surgical percutaneous interventions: 0, 1, or 2 events; serious adverse events: 0, 1, or 2 events.