Table 3.
Predictors included in the 17 prediction models.
| First Author (year) | Clinical symptoms | Laboratory Examination | Others |
|---|---|---|---|
| Kobayashi T (2006)21 |
Sodium ≤ 133 mmol/L AST ≥ 100 IU/L Neutrophils ≥ 80% CRP ≥ 10 mg/UL Platelet count ≤ 30.0 × 104/mm3 |
Dates of illness at initial treatment ≤ 4 day Age ≤ 12 months |
|
| Egami K (2006)25 |
Platelet count ≤30 × 1010/L CRP ≥ 8 mg/dL ALT ≥ 80 IU/L |
Infants younger than 6 months Before 4 days of illness |
|
| Yang S (2019)23 |
CRP ≥ 90 mg/L Neutrophil ≥ 70% Sodium ion concentration < 135 mmol/L Albumin < 35 g/L Total bilirubin > 20 μmol/L |
||
| Wu S (2020)28 |
NE ≥ 10 × 109/L LY ≤ 3 × 109/L MPV ≥ 10.5 fL ALB ≤ 37 g/L |
Age ≤ 24 months | |
| Piram M (2020)19 | Hepatomegaly |
ALT > 30 IU/L Lymphocyte count < 2400/mm3 |
Time to treatment < 5 days |
| Wu S (2019)32 |
Peripheral NLR ≥ 2.69 MPVLR ≥ 2.78 Serum albumin ≤ 30.7 g/L Serum sodium ≤ 135.2 mmol/L |
||
| Fu PP (2013)33 |
Polymorphous Exanthema; Changes around anus |
CRP ≥ 8 mg/dL Neutrophils ≥ 80% |
Days of illness at initial treatment |
| Gámez-González LB(2018)26 |
Pre HR > 146 bpm; Pre BT > 38.8 °C |
Neutrophils > 80% Albumin <3.4 g/dL AST > 100 IU/L |
|
| Tan XH (2019)18 |
D-CALs; Na; TBA; P-LYM; PLT RDW, ALB |
Age | |
| Bar-Meir M (2018)20 | Coronary artery abnormalities | Days of illness at presentation <5 | |
| Wang T (2021)24 | Body weight |
Platelet count; blood calcium; albumin-to-globulin ratio; total bilirubin; cholesterol |
Days of fever prior to hospitalization |
| Tang Y (2016)27 |
Rash Edema of extremities |
Neutrophils ≥ 80% Serum albumin < 35 g/L |
Age < 6 months |
| Hua W (2017)34 |
Sodium ≤ 135 mmol/L NLR ≥ 1.9 Platelet ≤ 350 × 109/L GGT ≥ 25 U/L |
Total fever duration ≥ 7 days Delayed diagnosis |
|
| Sano T (2006)35 |
CRP ≥ 7.0 mg TB ≥ 0.9 mg AST ≥ 200 IU/L |
||
| Tremoulet AH (2008)30 |
% Bands ≥ 20 GGT ≥ 60 zHgb ≤ −2 |
Illness day ≤ 4 | |
| Lin, M. T (2016)22 | Positive lymphadenopathy |
Albumin < 3.5 g/dL Neutrophil percentage ≥ 60% |
|
| Sato S (2013)17 |
Neutrophil percentage ≥ 75% IL-6 level ≥ 140 pg/mL IL-6 level ≥ 70 pg/mL but ≤ 140 pg/mL |
CRP C-reactive protein, ALT alanine aminotransferase, AST aspartate aminotransferase, NE peripheral neutrophil count, MPV peripheral mean platelet volume, LY peripheral lymphocyte count, ALB serum albumin, NLR neutrophil-to-lymphocyte ratio, MPVLR mean platelet volume-to-lymphocyte ratio, P-LYM percentage of lymphocyte, RDW red blood cell distribution width, TBA total bile acid, D-CALs degree of coronary artery lesions, zHgb Age-adjusted hemoglobin, TB total bilirubin, GGT γ-glutamyl transferase.