Why did we carry out this study?

Tianeptine is an atypical tricyclic antidepressant used in other countries for treating major depressive disorder; however, it is not approved for use in the United States.

Tianeptine has agonist activity at opioid receptors and can be misused for its euphoric highs.

This study was carried out to see what the literature says about the scope of the problem with tianeptine use, given its easy accessibility.

What was learned in the study?

Overdose and use in suicide attempts occur when used in combination with other substances.

Tolerance and withdrawal can occur in those who use the substance.

Treatment options for opioid use may include medications such as buprenorphine, among others.

Further studies should be conducted to gain a deeper understanding of this substance.