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. 2023 Aug 8;12(5):1553–1572. doi: 10.1007/s40120-023-00530-4
This meta-analysis evaluated the clinical efficacy of tenecteplase and alteplase in the treatment of AIS.
Tenecteplase is more effective than alteplase in patients with AIS.
There was no difference in safety between tenecteplase and alteplase in patients with AIS.
Further high-quality RCTS are needed to confirm the superiority of tenecteplase over alteplase in the treatment of AIS.