Table 2.
Comparison of thyroid function indicators in young MDA patients with and without suicide attempts.
| MDA without suicide attempts group (n = 321) | MDA with suicide attempts group (n = 146) | t/χ2/z | p | |
|---|---|---|---|---|
| TSH (mIU/mL, Mean ± SD) | 4.73 ± 2.55 | 6.68 ± 2.95 | − 7.290 | < 0.001 |
| TSH Decrease (< 0.27 mIU) | 0 | 0 | 13.158 | < 0.001 |
| TSH Normal (0.27–4.20 mIU/L) | 140 (43.6%) | 38 (26%) | ||
| TSH Increase (> 4.20 mIU/L) | 181 (56.4%) | 108 (74%) | ||
| FT3 (pmol/L, Mean ± SD) | 4.97 ± 0.69 | 4.90 ± 0.81 | 0.938 | 0.349 |
| FT3Decrease (< 3.10 pmol/L) | 0 | 0 | 2.203 | 0.138 |
| FT3Normal (3.10–6.8 pmol/L) | 321 (100%) | 145 (99.3%) | ||
| FT3Increase (> 6.8 pmol/L) | 0 | 1 (0.7%) | ||
| FT4 (pmol/L, Mean ± SD) | 16.65 ± 3.03 | 16.95 ± 3.33 | − 0.862 | 0.389 |
| FT4Decrease (< 10 pmol/L) | 0 | 0 | 0.914 | 0.339 |
| FT4Normal (10–23 pmol/L) | 319 (99.4%) | 146 (100%) | ||
| FT4Increase (> 23 pmol/L) | 2 (0.6%) | 0 | ||
| TgAb (IU/L, Mean ± SD) | 92.08 ± 244.84 | 137.86 ± 290.37 | − 3.703 | < 0.001 |
| TgAb Normal (0–115 IU/L) | 270 (84.1%) | 102 (69.9%) | 12.574 | < 0.001 |
| TgAb Increase (> 115 IU/L) | 51 (15.9) | 44 (30.1%) | ||
| TPOAb (IU/L, Mean ± SD) | 52.10 ± 98.02 | 133.84 ± 236.47 | − 3.378 | 0.001 |
| TPOAb Normal (0–34 IU/L) | 247 (76.9%) | 84 (57.5%) | 18.322 | < 0.001 |
| TPOAb Increase (> 34 IU/L) | 74 (23.1%) | 62 (42.5%) |
MDA major depressive disorder patients with comorbid anxiety, TSH thyroid stimulating hormone, FT3 free triiodothyronine, FT4 free thyroxine, TgAb anti-thyroglobulinand, TPOAb thyroid peroxidases antibody.