Table 4.
The angioinvasion and metastasis regression analysis.
| Parameter | B | SE | p | OR (95% CI) |
|---|---|---|---|---|
| The biochemical profile | ||||
| CHOL | 0.016 | 0.007 | < 0.05 | 1.016 (1.004–1.032) |
| LDL | 0.033 | 0.011 | < 0.05 | 1.034 (1.015–1.058) |
| TG | 0.002 | 0.003 | NS | 1.002 (0.995–1.008) |
| HDL | − 0.041 | 0.022 | < 0.05 | 0.960 (0.915–0.998) |
| GLUCOSE | − 0.001 | 0.012 | NS | 0.999 (0.968–1.022) |
| CRP | − 0.082 | 0.095 | NS | 0.921 (0.706–1.054) |
| 25-OH VIT D | 0.001 | 0.022 | NS | 1.001 (0.955–1.043) |
| TGB | 0.238 | 0.355 | NS | 1.269 (0.984–2.678) |
| TGBAb | 0.003 | 0.009 | NS | 1.003 (0.981–1.021) |
| TSH | − 0.046 | 0.050 | NS | 0.955 (0.822–1.025) |
| FT3 | − 0.008 | 0.373 | NS | 0.995 (0.451–2.064) |
| FT4 | 0.207 | 0.876 | NS | 1.230 (0.216–7.119) |
| The oxidative stress markers | ||||
| TOC | − 0.0001 | 0.001 | NS | 0.100 (0.997–1.002) |
| TAC | − 0.014 | 0.006 | < 0.05 | 0.986 (0.974–0.997) |
| MDA | 0.004 | 0.002 | NS | 1.004 (0.100–1.008) |
| DNA/RNA OSDP | 0.005 | 0.003 | < 0.05 | 1.005 (1.000–1.011) |
| IL-6 | 0.097 | 0.227 | NS | 1.102 (0.691–1.718) |
| SIRT1 | 0.142 | 0.264 | NS | 1.152 (0.666–1.971) |
| SIRT3 | − 0.458 | 0.200 | < 0.05 | 0.633 (0.408–0.896) |
| NF-κB | − 1.636 | 2.418 | < 0.05 | 0.195 (0.001–14.280) |
| FOXO | − 0.379 | 0.443 | NS | 0.684 (0.225–1.440) |
| DNA methylation | − 0.018 | 0.039 | NS | 0.982 (0.907–1.060) |
| PRKAA1 | 0.351 | 0.349 | NS | 1.421 (0.713–3.044) |
| PGC1α | 0.619 | 0.533 | NS | 1.857 (0.654–5.470) |
| p53 | − 0.0001 | 0.001 | NS | 1.000 (0.999–1.001) |
CHOL cholesterol, CRP C-reactive protein, PTC papillary thyroid cancer, fT3 free triiodothyronine, fT4 free thyroxine; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TG, triglyceride; TGB, thyroglobulin; TGBAb antithyroglobulin antibodies; TSH, thyroid-stimulating hormone; VIT D, vitamin D; IL-6, interleukin 6; FOXO, Forkhead box O family member proteins; NF-κB, nuclear factor kappa B; MDA, malondialdehyde, p53, protein 53, SIRT1, Sirtuin 1; SIRT3, Sirtuin 3; TAC, total antioxidant capacity; TOC, total oxidative capacity; PRKAA1 5′-AMP-activated protein kinase catalytic subunit alpha-1; PGC1α, peroxisome proliferator-activated receptor gamma coactivator 1-alpha; MDA, malondialdehyde; DNA/RNA DNA/RNA oxidative stress damage products; B beta, SE, standard error; p, p-value; OR, odd ratio.