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Results of the cytotoxic activity of compounds 10i,10o and sorafenib against THLE-2 normal cell line as CC50 in μM and their calculated selectivity index (SI) for HepG2 cancer cell line.
| Compound | CC50a | SIb |
|---|---|---|
| 10i | 21.00 | 13.13 |
| 10o | 15.18 | 5.52 |
| Sorafenib | 18.49 | 2.20 |
aCC50: Cytotoxic activity against THLE-2 normal cell line in μM; measured in triplicates.
bSI: Selectivity index calculated as CC50/IC50.
