Table 7.

Pharmacokinetic prediction results of compounds 10i using Biovia Discovery Studio.

Parameter	10i
GIT absorption	1
Blood Brain permeability	4
Cytochrome P450 2D6	False
Absorption: 0 (Good), 1 (Moderate), 2 (Poor), 3 (Very poor)
BBB permeability: 0 (Very high), 1 (High), 2 (Medium), 3 (Low), 4 (Undefined)