Skip to main content
. 2023 Aug 22;13:13670. doi: 10.1038/s41598-023-40868-1

Table 4.

Multivariable-adjusteda,b odds ratio (OR) and 95% confidence intervals (95% CIs) of NAFLD according to use of VMS according to demographic and lifestyle factors.

Stratification factors Cases/Non-cases Use of VMS P interaction
Nonusers Current users
OR (95% CI) OR (95% CI)
By aged
Age < 56 years 1,197/2,463 1 (Ref) 0.54 (0.40–0.72)  < .001
Age ≥ 56 years 818/2,898 1 (Ref) 1.23 (0.91–1.65)
By sex
Male 965/2,786 1 (Ref) 0.56 (0.40–0.80) 0.04
Female 1,050/2,575 1 (Ref) 0.99 (0.74–1.33)
By BMIe
BMI < 23 kg/m2 36/2,236 1 (Ref) 1.11 (0.43–2.86) 0.54
BMI ≥ 23 kg/m2 1,979/3,125 1 (Ref) 0.71 (0.56–0.90)
By smoking status
Never 1,113/2,864 1 (Ref) 0.90 (0.66–1.22) 0.15
Past 412/1,354 1 (Ref) 0.75 (0.47–1.20)
Current 490/1,143 1 (Ref) 0.44 (0.27–0.72)
By alcohol drinking status
Never 364/969 1 (Ref) 0.85 (0.51–1.42) 0.83
Past 304/787 1 (Ref) 1.06 (0.57–1.98)
Current 1,347/3,605 1 (Ref) 0.67 (0.51–0.88)
By fruit and vegetable consumptionf
 < 395.8 g/day 996/2,671 1 (Ref) 0.81 (0.57–1.16 0.46
 ≥ 395.8 g/day 1,019/2,690 1 (Ref) 0.69 (0.51–0.92)

BMI body mass index, CI confidence intervals, NAFLD non-alcoholic fatty liver disease, OR odds ratio, VMS vitamin and mineral supplements.

aAll results presented in this table are sampling-weighted estimates except the number of study participants.

bMultivariable model was adjusted for age (quartiles), sex (male, female), household income level (quartiles), education level (elementary school, middle school, high school, college or higher), smoking status (never, past, current), alcohol drinking status (never, past, ≤ 1 time/month, 2– ≤ 4 times/month, ≥ 2 times/week), regular exercise (no, yes), body mass index (< 18.5 kg/m2, 18.5– < 23 kg/m2, ≥ 23- < 25 kg/m2, ≥ 25 kg/m2), waist circumference (cm, continuous), diabetes mellitus (no, yes), hypercholesterolemia (no, yes), number of comorbidities (0, 1, 2, 3, ≥ 4), serum triglyceride concentration (mg/dL, continuous), hypertension stage (stage1, ≥ stage2, other), current use of hypertension medications (no, yes), and intakes of total energy (quartiles) and fruits and vegetables (quartiles).

cP interaction was tested by including the product term between current use of VMS and each of stratification factors.

dAge groups were defined using the median value of our study population as a cut-off value.

eBMI of 23 kg/m2 is the cut-off criteria to define overweight status in the Asian population.

fFruit and vegetable consumption groups were categorized using the median value of our study population as a cut-off value.