FIG. 1.
Outcome of HSV infection in β2KO (▵) and control (●) mice. The results show the fraction of mice surviving without neurological impairment (paralysis or gross motor ataxia) over time in days after bilateral footpad inoculation with 106 (left), 5 × 105 (middle), or 7.5 × 104 (right) PFU/footpad. The numbers of mice per group and P values by log rank test were 7 β2KO mice, 6 controls, and P of 0.004 for the group inoculated with 106 PFU; 20 β2KO mice, 16 controls, and a P of 0.002 for the group inoculated with 5 × 105 PFU; and 6 β2KO mice, 6 controls, and a P of 0.14 for the group inoculated with 7.5 × 104 PFU.