Patients with Dravet syndrome experience daily severe seizures with progressive deterioration in their physical, cognitive and behavioural development, which substantially impacts the quality of life of patients and their carers.

This study examined the relationship between seizures and patients’ and carers’ quality of life.

Regression analyses were conducted using data from the fenfluramine registration studies.

Each additional convulsive seizure-free day (per 28 days) increased the quality of life by 0.005 for patients and 0.014 for carers.

This study showed that improving convulsive seizure-free days through effective antiseizure treatment can directly improve patients’ and carers’ QoL.