Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jun 1;16(3):325–339. doi: 10.1016/j.jcmgh.2023.05.009

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Transmission electron microscopy of adult control and Sox9-deficient units reveals SOX9 is required for cells with mucous neck ultrastructure to develop. (A) Representative adult control corpus unit from pit to base. (B) Higher-magnification images of the neck region of a control unit. Green arrowheads, mucous neck cells; yellow arrowhead, parietal cells. (C) Higher-magnification image of a single neck cell. (D) Representative Sox9-deficient corpus unit, pit to base from an adult Fgf20^Cre.GFP/+ ; Sox9^fl/fl animal. (E) Higher-magnification images of the neck region of a Sox9-deficient unit. Blue arrowheads, primitive cells lacking ultrastructural features of any differentiated lineage; yellow arrowheads, parietal cells. (F) Higher-magnification image of a single primitive cell in the neck region of a Sox9-deficient unit. Scale bars: (A, B, D, and E) 4 μm; (C and F), 2 μm.