Skip to main content
. 2023 Aug 22;13(8):e1386. doi: 10.1002/ctm2.1386

TABLE 3.

Clinical trials of macrophage repolarization immunotherapy in gastric cancer.

Target Class Compound Combination/monotherapy Clinical phase/study type Sponsors/collaborators ClinicalTrials.gov ID no. Status
HER‐2 overexpressing tumours CAR‐macrophages CT‐0508 Monotherapy Phase 1/interventional National Center for Tumour Diseases, Heidelberg/University Hospital Heidelberg Carisma Therapeutics Inc. NCT04660929 Recruiting
CSF‐1/CSF‐1R axis CSF‐1 inhibitors MCS110 MCS110/PDR001 combination Phase 2/interventional Seoul National University Hospital NCT03694977 Recruiting
Claudin 18.2 and CD47 Claudin 18.2 and CD47 inhibitors PT886 Monotherapy Phase 1/interventional MD Anderson Cancer Center/Phanes Therapeutics NCT05482893 Recruiting