TABLE 3.
Target | Class | Compound | Combination/monotherapy | Clinical phase/study type | Sponsors/collaborators | ClinicalTrials.gov ID no. | Status |
---|---|---|---|---|---|---|---|
HER‐2 overexpressing tumours | CAR‐macrophages | CT‐0508 | Monotherapy | Phase 1/interventional | National Center for Tumour Diseases, Heidelberg/University Hospital Heidelberg Carisma Therapeutics Inc. | NCT04660929 | Recruiting |
CSF‐1/CSF‐1R axis | CSF‐1 inhibitors | MCS110 | MCS110/PDR001 combination | Phase 2/interventional | Seoul National University Hospital | NCT03694977 | Recruiting |
Claudin 18.2 and CD47 | Claudin 18.2 and CD47 inhibitors | PT886 | Monotherapy | Phase 1/interventional | MD Anderson Cancer Center/Phanes Therapeutics | NCT05482893 | Recruiting |