Table 2.
Pearson correlations between susceptibility MRI and histology metrics
| NM+ neuron density | Glial density | log(%AO α-synuclein) | log(%AO tau) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| r | df | P | r | df | P | r | df | P | r | df | P | |
|
| ||||||||||||
| R2* | −0.09 | 25 | 0.656 | 0.70 | 25 | <0.0001 * | −0.09 | 24 | 0.659 | 0.61 | 23 | 0.001 * |
| QSM | 0.05 | 25 | 0.812 | 0.67 | 25 | <0.001 * | −0.01 | 24 | 0.945 | 0.53 | 23 | 0.007 |
Pearson correlation coefficients (r) between susceptibility MRI and histology metrics with degrees of freedom (df) and unadjusted probability values (P).
P < 0.05 are bolded.
*
P < 0.00625 to correct for multiple comparisons.
Abbreviations: NM+ = neuromelanin-positive; %AO = percent of area occupied by positive staining; R2* = apparent transverse relaxation rate; QSM = quantitative susceptibility mapping.