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. 2023 Aug 9;14:1162473. doi: 10.3389/fimmu.2023.1162473

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Copyright © 2023 Huang, Wang, Chen, Chai, Qi, Zheng, Chen, Wu and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Examination of biomarkers in CD fibrosis rats. Representative HE stained and Masson stained images in normal (A, C) and model groups (B, D), scale bar = 200µm. Statistical analysis of the expression levels of COL1A1、MMP2、CXCL10 and FGF2 in the control and model groups based on the RT-PCR assay (E–H). Control: blank control rats (n=6); CD fibrosis, Crohn’s disease fibrosis model group rats (n=6). Data are presented as the mean ± SD. **p< 0. 05, ***p< 0.01, ns, no significant difference.