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. 2023 Aug 9;10:1235942. doi: 10.3389/fvets.2023.1235942

Table 4.

Vaccination timing and vaccine type for all vaccine doses administered to weaned and suckling calves for common vaccine targets used in 131 Canadian cow-calf herds.

Vaccination timing BVDV types 1 or 2 IBR, BRSV, and PI3 Mh +/− Pm a H. somni Clostridia spp.
Suckling calves
Birth – 2 weeks 0 (0) 0.21 (27) 0.07 (9) 0 (0) 0.04 (5)
2 weeks – 3 months 0.50 (65) 0.60 (79) 0.42 (55) 0.31 (40) 0.67 (88)
>3 months 0.52 (68) 0.62 (81) 0.40 (53) 0.23 (30) 0.42 (55)
Modified live vaccine 0s.75 (98) 0.91 (119) 0.18 (23) n/a n/a
Birth – 2 weeks (0) 0.20 (26) 0.07 (9) n/a n/a
2 weeks – 3 months 0.49 (64) 0.60 (78) 0.08 (11) n/a n/a
>3 months 0.50 (65) 0.62 (81) 0.08 (10) n/a n/a
Inactivated/killed vaccine 0.03 (4) 0.02 (2) 0.47 (61) 0.40 (52) 0.87 (114)
Birth – 2 weeks 0 (0) 0.01 (1) 0.01 (1) 0 (0) 0.04 (5)
2 weeks – 3 months 0.01 (1) 0.01 (1) 0.34 (44) 0.31 (40) 0.67 (88)
>3 months 0.02 (3) 0 (0) 0.33 (43) 0.23 (30) 0.42 (55)
Intranasal vaccine n/a 0.33 (43) 0.10 (13) n/a n/a
Birth – 2 weeks n/a 0.20 (26) 0.07 (9) n/a n/a
2 weeks – 3 months n/a 0.14 (18) 0.03 (4) n/a n/a
>3 months n/a 0.03 (4) 0.01 (1) n/a n/a
Weaned calves
At weaning 0.40 (52) 0.40 (52) 0.20 (26) 0.16 (21) 0.20 (26)
After weaning 0.27 (35) 0.23 (30) 0.16 (21) 0.08 (11) 0.09 (12)
Modified live vaccine 0.56 (73) 0.57 (75) 0.05 (6) n/a n/a
At weaning 0.38 (50) 0.41 (54) 0.02 (3) n/a n/a
After weaning 0.26 (34) 0.21 (28) 0.02 (3) n/a n/a
Inactivated/killed vaccine 0.02 (3) 0.02 (2) 0.30 (39) 0.27 (21) 0.27 (36)
At weaning 0.02 (2) 0.01 (1) 0.18 (23) 0.16 (21) 0.20 (26)
After weaning 0.01 (1) 0.02 (2) 0.14 (18) 0.08 (11) 0.09 (12)
Intranasal vaccine n/a 0.02 (3) 0 (0) n/a n/a
At weaning n/a 0.02 (3) 0 (0) n/a n/a
After weaning n/a 0.01 (1) 0 (0) n/a n/a

Reported as proportion of herds that vaccinated (number of herds).

a

Mannheimia haemolytica with or without Pasteurella multocida; n/a = not applicable: no registered MLV vaccine available for listed bacterial target.