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. 2023 Aug 9;14:1162786. doi: 10.3389/fendo.2023.1162786

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Copyright © 2023 Collins, Wang, Klymenko, Davis, Martinez, Zhang, So, Buechlein, Rusch, Creighton and Hawkins

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Molecular comparison of cell line transcriptomic profiles with clinical samples. Computational analysis of the molecular similarity of the clinical samples (Eoma, benign endometrioma or OCCC, OCCC with concurrent endometriosis) and cell lines from CCLE. A pathway activation score (PAS) was first computed for each pathway and each sample. Then the similarity between the samples was assessed by Pearson Correlation Coefficients (PCC) of the PAS. Cell line nomenclature is the CCLE name of the line_tissue type. A yellow color represents a higher PCC; blue, a lower PCC.