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. 2023 Aug 9;14:1162786. doi: 10.3389/fendo.2023.1162786

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Copyright © 2023 Collins, Wang, Klymenko, Davis, Martinez, Zhang, So, Buechlein, Rusch, Creighton and Hawkins

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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OCCC with concurrent endometriosis is molecularly distinct from benign endometrioma using miRNA expression. (A) Principal component (PC) analysis of malignant OCCC with concurrent endometriosis (triangles, OCCC) clusters separately from benign endometrioma samples (circles, Eoma), using PC1 and PC2. (B) Volcano plot of the significantly dysregulated miRNAs. Red represents miRNAs with P< 0.05, log2 fold-change > |1|. Blue dots represent miRNAs log2 fold-change > |1|. Green represents miRNAs with P< 0.05. Purple dots represent non-statistically significant miRNAs. The labeled dot represents hsa-miR-10a-5p.