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. 2023 Aug 9;14:1162786. doi: 10.3389/fendo.2023.1162786

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Copyright © 2023 Collins, Wang, Klymenko, Davis, Martinez, Zhang, So, Buechlein, Rusch, Creighton and Hawkins

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MiR-10a-5p expression across a panel of ovarian cancer cell lines. (A) RQ, the relative quantity of hsa-miR-10a-5p to U6 snRNA, normalized to A2780. ***P<0.001, **P<0.001, *P< 0.05, Brown-Forsythe and Welch ANOVA. A2780 (n = 6), A2780CR5 (n = 2), SKOV3ip1 (n = 3), RMG-I (n = 2), SKOV3 (n = 4), OVAS (n = 4), ES-2 (n = 4), OVISE (n = 9), TOV-21G (n = 4), OVTOKO (n = 7), KK (n = 3), and SMOV-2 (n = 6). (B) Correlation of miR-10a-5p expression to carboplatin IC50 in OCCC cell lines. RMG-I (n = 2), OVAS (n = 4), ES-2 OVISE (n = 9), TOV-21G (n = 2), OVTOKO (n = 7), KK (n = 2), and SMOV-2 (n = 6). Carboplatin IC50 is n ≥ 5 for each cell line.