Table 2.
Baseline Clinical Characteristics of Studied Children and Eyes With and Without Adjuvant Chemotherapy
| Characteristic | With Adjuvant Chemotherapy (n = 48) | Without Adjuvant Chemotherapy (n = 12) | P Value |
|---|---|---|---|
| Sex | |||
| Male | 26 (54%) | 7 (58%) | 0.749 |
| Female | 22 (46%) | 5 (42%) | |
| Age of diagnosis (mo) | |||
| Median | 20 | 20 | 0.897 |
| Range | 2–76 | 5–44 | |
| Laterality | |||
| Unilateral | 43 (90%) | 10 (83%) | 0.546 |
| Bilateral | 5 (10%) | 2 (17%) | |
| Enucleation | |||
| Primary | 20 (42%) | 2 (17%) | 0.108 |
| Secondary | 28 (58%) | 10 (83%) | |
| IIRC of studied eye | |||
| D | 17 (35%) | 10 (83%) | 0.012* |
| E | 30 (63%) | 2 (17%) | |
| Unknown | 1 (2%) | 0 | |
| AJCC cTNM of studied eye | |||
| cT2b | 17 (35%) | 10 (84%) | 0.054 |
| cT3b | 8 (17%) | 1 (8%) | |
| cT3c | 9 (19%) | 0 | |
| cT3d | 13 (27%) | 1 (8%) | |
| Unknown | 1 (2%) | 0 |
IIRC = International Intraocular Retinoblastoma Classification; AJCC = American Joint Committee on Cancer.