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. 2023 Aug 9;36(8):1238–1247. doi: 10.1021/acs.chemrestox.2c00378

Table 6. TG-GATEs Observed Phenotype Counts.

  Phenotype N
1 apoptosis 2
2 apoptosis/single cell necrosis 1
3 atypia nuclear 1
4 bile duct hyperplasia 4
5 cytoplasmic alteration basophilic change/ 6
  glycogen depletion  
6 cytoplasmic alteration eosinophilic 17
7 cytoplasmic alteration glycogen accumulation 4
8 degeneration hydropic 2
9 fibrosis 2
10 focus of cellular alteration basophilic 1
11 focus of cellular alteration clear cell 1
12 hepatocellular adenoma 1
13 hepatocellular atrophy 1
14 hypertrophy and vacuolation 1
15 hypertrophy hepatocellular 48
16 hypertrophyhyperplasia 9
17 inclusions cytoplasmic 2
18 increased mitoses 4
19 karyocytomegaly 1
20 necrosis 1
21 necrosis zonal 2
22 oval cell hyperplasia 1
23 pigmentation pigment deposition 3
24 prominent nucleoli 1
25 single cell necrosis 10
26 vacuolation 19
27 vacuolation lipid 3