Algorithm 1.

DeepGlioma patient-level molecular subgroup prediction

Require: $p(y\mid 𝓧),\tau ,\psi ,ϵ▷\tau =0.5,\psi =1$ for DeepGlioma experiments
1:	${\widehat{y}}_{mol}\Leftarrow \varnothing$
2:	if $p\left(y=k_{IDH}\mid 𝓧\right)<\tau$ then
3:	${\widehat{y}}_{mol}\Leftarrow$ ‘Glioblastoma, IDH-wildtype’
4:	else if $p\left(y=k_{IDH}\mid 𝓧\right)\ge \tau \text{\&}\frac{p\left(y=k_{1p19q}\mid 𝓧\right)}{p\left(y=k_{ATRX}\mid 𝓧\right)+ϵ}>\psi$ then
5:	${\widehat{y}}_{mol}\Leftarrow$ ‘Oligodendroglioma, IDH-mutant, and 1p19q-codeleted’
6:	else if $p\left(y=k_{IDH}\mid 𝓧\right)\ge \tau \text{\&}\frac{p\left(y=k_{1p19q}\mid 𝓧\right)}{p\left(y=k_{ATRX}\mid 𝓧\right)+ϵ}\le \psi$ then
7:	${\widehat{y}}_{mol}\Leftarrow$ ‘Astrocytoma, IDH-mutant’
8:	end if
9:	return ${\widehat{y}}_{mol}$