Table 2.

Model input for costs.

Cost ($2,022)	N+C	L+C	SA range	Distribution
Cost of chemotherapeutics
Neratinib (per 40 mg)	13.46		12.114–14.806	Gamma
Lapatinib (per 250 mg)	16.12		14.508–17.732	Gamma
Capecitabine (per 150 mg)	0.6		0.540–0.660	Gamma
Total	10176.6	11541.6
Cost of AEs
Loperamide (per 2 mg)	0.23		0.207–0.253	Gamma
Diarrhea (per event)	4083.63		3675.267–4491.993	Gamma
PPE syndrome (per event)	2316		2084.400–2547.600	Gamma
Vomiting (per event)	945.63		851.067–1040.193	Gamma
Fatigue (per event)	1158.04		1042.236–1273.844	Gamma
Anemia (per event)	7350.98		6615.882–8086.078	Gamma
Total	16183.38	15854.28
Cost for others
Hospitalization	3200		2880.000–3520.000	Gamma
Concomitant medications	2176		1958.400–2393.600	Gamma
Health examinations	4552		4096.800–5007.200	Gamma
Total	9928	9928

AEs, advanced events. PPE, Palmar-Plantar Erythrodysesthesia.